In a new study, it is evident that Platelet-Rich Plasma is considerable superior to Hyaluronic Acid in treatment for gonarthrosis (arthritis of the knee). Patients that underwent PRP had decreased pain, stiffness and functional limitations such as walking, stair use, standing, and bending etc when compared to patients who were given HA therapy. This difference was even more significant in patients with grade III (severe) knee arthritis. In these patients HA therapy was not effective while PRP provided same positive results regardless of the severity. Patients reported drastic effect soon after receiving the fourth and final PRP injection and continued to show improvement up to 24 weeks.