A study from Istanbul, Turkey looked at the effects of cigarette smoking on the viability of platelets. Platelets are very fragile and special care must be taken in preparing them for injection after increasing their concentration. However, research suggests that smokers may have increased free radicals that affect the oxidant/anti-oxidant balance, thus reducing platelet activity.
www.blackwell-synergy.com/doi/abs/10.1080/13556210020077046
Future research should compare the platelet concentration & clinical effects of PRP in non-smokers Vs smokers.