Posts Tagged ‘tendon injuries’
Tuesday, August 28th, 2012 by Beny Charchian, M.D., M.S.
AARP Magazine recently featured several breakthrough therapies for treating tendon injuries including Prolotherapy and Platelet Rich Plasma (PRP).
Prolotherapy is a treatment that utilizes dextrose, a type of sugar, to serve as an irritant to awaken and speed up our body’s own natural healing capacities. Prolotherapy induces changes within weakened tendons to increase strength and firmness. Treatments generally involve a series of injections under the guidance of an ultrasound for proper placement. This therapy has become increasingly popular as both patients and doctors shy away from using cortisone for tendon injuries because of the potential damage steroids can inflict upon already weakened tendons.
Tendon injuries can also be treated with Platelet Rich Plasma, or PRP. PRP is derived from a patient’s own blood and is also a more natural way to treat injuries compared to steroids. Platelets have been shown to be rich in growth factors – which is what our body uses to heal an injured area. Spinning of a patient’s blood in device called a centrifuge allows these growth factors to become concentrated. This concentrate of platelets and growth factors, called PRP, is then injected back into an injured area to stimulate natural healing and tissue regeneration. PRP has been shown to be beneficial in more than tendon injuries as promising results have also been seen in clinical trials including ligaments, muscle, and cartilage.
The doctors of the Orthohealing Center have treated hundreds of patients with Prolotherapy and PRP with very encouraging results. We are delighted to see AARP Magazine helping to spread the knowledge of these cutting-edge therapies!
Tags: AARP Magazine, platelet rich plasma, Prolotherapy, PRP, tendon injuries
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Dr. Charchian specializes in Interventional Pain Management integrating Fluoroscopy (live X-Ray), in addition to treating an array of spine and joint disorders non-surgically. He has extensive training in electrodiagnostic studies to evaluate nerve injuries. He completed a Pain Medicine Fellowship at UCLA and is currently a Clinical Instructor of Medicine at The David Geffen School of Medicine at UCLA as well as a Clinical Assistant Professor of Physical Medicine & Rehabilitation, Western University of Health Sciences.
Friday, June 8th, 2012 by Beny Charchian, M.D., M.S.
Platelet Rich Plasma and Bone Marrow Concentrate injections are becoming increasingly popular in the world of Orthopedics as a safe and effective alternative to surgery.
Recently, the use of Fibrin as an addition to these regenerative injections has gained attention as way to increase response to the healing properties of these treatments.
Fibrin is the body’s first response to injury and pain. It is an insoluble protein shaped like long threads which interlace to form a thin mesh around an injured area. This mesh then serves as a scaffold for platelets to attach and adhere. When used in regenerative injections, fibrin is isolated and purified from the patient’s own platelet poor plasma (PPP), which used to be discarded before researchers realized the healing power of fibrin! Given in combination with platelet rich plasma or bone marrow concentrate injections, the addition of fibrin offers a more robust response of healing and tissue regeneration.
At the Orthohealing Center, we strive to stay on the cutting edge of medicine by providing our patients with the newest non-surgical options to treat a wide array of joint, tendon, and ligament injuries.
Tags: Bone Marrow Concentrate, Bone Marrow Concentrate injections, joint injuries, ligament injuries, platelet rich plasma, tendon injuries
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Dr. Charchian specializes in Interventional Pain Management integrating Fluoroscopy (live X-Ray), in addition to treating an array of spine and joint disorders non-surgically. He has extensive training in electrodiagnostic studies to evaluate nerve injuries. He completed a Pain Medicine Fellowship at UCLA and is currently a Clinical Instructor of Medicine at The David Geffen School of Medicine at UCLA as well as a Clinical Assistant Professor of Physical Medicine & Rehabilitation, Western University of Health Sciences.
Friday, September 23rd, 2011 by Steven Sampson D.O.
We were honored to have worldwide leading scientists in clinical research for tendons visit the Orthohealing Center this week. Chronic tendon injuries termed “Tendinopathies” are stubborn to heal due to many factors including repitive activity & poor blood flow.
With our new understanding that there is not a strong “inflammatory response”, comes a whole realm of treatments to directly target this disease. It’s critical that patients have the appropriate nutritional & cellular balance to facilitate healing.
Scientists at Bioberica are leading the way in tendon research with innovative products to influence healing in unimaginable ways. We hope to conduct data to better understand this perplexing yet frequently occuring condition.
Thank you to our patients for allowing the Spanish research team to observe bedside interactions.
Tags: Bioberica, Carlos Chetrit-Russi, Daniel Martinez Puig DVM PhD, Dr Beny Charchian, Dr Danielle Aufiero, Dr. Steve Sampson, Jaime Reguant, los angeles, Maria Vilaro PhD, orthopaedics, Spain, tendon injuries, tendonopathy, The Orthohealing Center
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Founder of the Orthohealing Center, Dr. Sampson is a recognized expert on orthobiologics and regenerative medicine. He lectures internationally and spearheads OHC’s clinical research efforts. Dr. Sampson is a Clinical Instructor of Medicine at The David Geffen School of Medicine at UCLA, and is a Clinical Assistant Professor of Physical Medicine & Rehabilitation, Western University of Health Sciences.
Monday, August 1st, 2011 by Steven Sampson D.O.
We’re excited announce, Dr Sampson’s next lecture will be at the Kaiser Permanente hosted Combined Symposium for Physical Medicine & Rehabilitation, Pain Management, & Occupational Medicine, Aug 6th 2011 in Los Angeles CA. Dr Sampson will speak on Platelet Rich Plasma (PRP) for musculoskeletal conditions (tendons, ligaments, cartilage/joints etc). Appx 150 health care professionals are expected to attend to learn more about this emerging therapy & the field of orthobiologics!
Tags: Dr. Steve Sampson, Kaiser Permanante, knee cartilage, los angeles, osteoarthritis, PRP, prp injection, prp lecture, Steven Sampson D.O., tendon injuries, tendonopathy
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Founder of the Orthohealing Center, Dr. Sampson is a recognized expert on orthobiologics and regenerative medicine. He lectures internationally and spearheads OHC’s clinical research efforts. Dr. Sampson is a Clinical Instructor of Medicine at The David Geffen School of Medicine at UCLA, and is a Clinical Assistant Professor of Physical Medicine & Rehabilitation, Western University of Health Sciences.
Thursday, March 31st, 2011 by Steven Sampson D.O.
The March 2011 edition of The American Journal of Sports Medicine published an article that showed superior results in pain and function from PRP Platelet Rich Therapy Injection compared to a cortisone shot at 2 year follow up. The controlled blinded study is the largest of it’s kind involving 2 Dutch teaching Hospitals. Overall 100 patients with tennis elbow (lateral epicondylitis) were involved in the study.
More & more studies are emerging on PRP therapy. Not all will be positive do the the variablity of study design, injection technique with or without ultrasound or x-ray guidance, platelet concentration, and severity of existing injury.
Nonetheless we’ve seen this procedure come along way in the nearly 5 years since we began conducting research & treating patients with PRP. We are principal investigators in the largest US controlled & blinded clinical trial on PRP involving 12 centers to determine if PRP injections are a safe & effective treatment for tennis elbow. Enrollment has been complete for almost 2 months with 230 patients.
A recent study in Orthopedics also demonstrated efficacy in PRP treatment for golfers & tennis elbow.
Performing reserach takes lots of time & resources, however as clinicians we have a responsibility to document our work & add the the field of regenerative medicine to maximize benefits & safety to our patients. There is much skepticism in the media regarding this novel therapy & many others. What most don’t realize is that publishing a 2 year study of this magnitude requires considerable time & resources. Congrats to the authors. Our 1 year knee arthritis PRP study took years to reach publication with lack of resouces etc.
Tags: Dr Danielle Aufiero, Dr Steven Sampson, Gosens, knee arthritis, lateral epicondylitis, osteoarthritis, Peerbooms, platelet rich plasma, Platelet Rich Plasma Therapy, PRP, prp injection, tendon injuries, tennis elbow, The american journal of sports medicine, The Orthohealing Center
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Founder of the Orthohealing Center, Dr. Sampson is a recognized expert on orthobiologics and regenerative medicine. He lectures internationally and spearheads OHC’s clinical research efforts. Dr. Sampson is a Clinical Instructor of Medicine at The David Geffen School of Medicine at UCLA, and is a Clinical Assistant Professor of Physical Medicine & Rehabilitation, Western University of Health Sciences.
Monday, February 28th, 2011 by Steven Sampson D.O.
A Feb 2011 study( Platelet Rich Plasma Injection reduces Pain in Patients with recaclitrant Epicondylitis) in ORTHOPEDICS; demonstrated efficacy of a single PRP injection to stubborn tennis & golfer’s elbow termed “epicondylitis.”
All 31 patients had continued pain for at least 6months and failed cortisone injection & physical therapy which are often associated with temporary benefit. 90% (28 out of 31) achieved successful outcome with reduction of at least 25% of their worst pain at 6month follow up. The study was limited because there was no control group that did not receive an injection or a placebo with anesthetic. However more & more studies are emerging that support the use of PRP for non-healing tendon injuries as an alternative to surgery.
We are principal investigators on an ongoing FDA approved clincial trail on PRP use for tennis elbow with 12 centers accross the US to determine if PRP use is safe & effective for tennis elbow. The enrollment is complete & results are soon to follow.
Again, PRP is not a Panacea & with time & quality trials we’ll learn what role platelet rich plasma will play in old and new injuries of muscle, tendon, and cartilage. Recently, PRP is being combined with a patient’s own stem cells derived from bone marrow & fat for more challenging cases with encouraging results. It is believed that the PRP acts as a rich environment to support & direct healing from other cell based therapies including stem cells.
Tags: golfers elbow, orthopedics, Platelet Rich Plasma Therapy, PRP, prp injection, stem cell, tendon injuries, tennis elbow, The Orthohealing Center
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Founder of the Orthohealing Center, Dr. Sampson is a recognized expert on orthobiologics and regenerative medicine. He lectures internationally and spearheads OHC’s clinical research efforts. Dr. Sampson is a Clinical Instructor of Medicine at The David Geffen School of Medicine at UCLA, and is a Clinical Assistant Professor of Physical Medicine & Rehabilitation, Western University of Health Sciences.
Sunday, December 13th, 2009 by Steven Sampson D.O.
In a recent newsletter to the community, Harvard University
discusses Platelet Rich Plasma Therapy. Overall there is a consensus that the treatment is promising, however more controlled studies are needed. Over the last 3 years there has been an increased awareness with this treatment. While the research is being conducted (which takes years to complete & publish), it’s good to see that Harvard recognizes that many patients are inquiring about this treatment in orthobiologics.
Tags: Dr Danielle Aufiero, Dr Steven Sampson, Harvard, Platelet Rich Plasma Therapy, PRP, prp injection, research, tendon injuries
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Founder of the Orthohealing Center, Dr. Sampson is a recognized expert on orthobiologics and regenerative medicine. He lectures internationally and spearheads OHC’s clinical research efforts. Dr. Sampson is a Clinical Instructor of Medicine at The David Geffen School of Medicine at UCLA, and is a Clinical Assistant Professor of Physical Medicine & Rehabilitation, Western University of Health Sciences.
Saturday, May 2nd, 2009 by Steven Sampson D.O.
With the timing of the Kentucky Derby today, there has been recent press about PRP therapy & stem cell usage in athletic horses. 
A company called VetCell’s from the UK just announced a Stem Cell Technique to Undergo Human Trials. They have treated over 1500 horses successfully & are now applying this stem cell technology to humans. I expect many studies in the next few years which will enlighten us exactly how we can maximize natural healing utilizing stem cells.
http://www.thehorse.com/ViewArticle.aspx?ID=13991&src=RA
Another study from Cornell University was just published on PRP use with horses showing effectiveness of healing tendon injuries. Tendon injuries are an important cause of catastrophic injury in athletic horses, and even minor injuries are often slow to heal and prone to future injury. Researchers performed ultrasound examinations of the tendons at 0, 2, 4, 6, and 8 weeks and mechanical, biochemical, and microscopic evaluation of the tendons 8 weeks after treatment.
Ultrasound while commonly used to look at babies, is seeing increased use in orthopedics and sports medicine to diagnose tendon injuries and to guide needle injections to ensure precise accuracy.
See Here.
Tags: Dr Steven Sampson, horse arthritis, kentucky derby, platelet rich plasma, PRP, prp injection, racehorses, research, tendon injuries
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Founder of the Orthohealing Center, Dr. Sampson is a recognized expert on orthobiologics and regenerative medicine. He lectures internationally and spearheads OHC’s clinical research efforts. Dr. Sampson is a Clinical Instructor of Medicine at The David Geffen School of Medicine at UCLA, and is a Clinical Assistant Professor of Physical Medicine & Rehabilitation, Western University of Health Sciences.
Monday, January 14th, 2008 by Steven Sampson D.O.
A new article from the Journal of Cellular Physiology presented some new insights into the role of PRP in tendon healing. After injecting PRP into mice patellar tendons, accelerated healing was demonstrated. The PRP had an 8.8 times platelet concentration above baseline versus whole blood.
Circulation derived cells play a key role in tendon healing. Blood flow is very important in connective tissue regeneration. Tendons typically have a poor blood supply (only 1/3 of the amount found in muscles). This study showed increased quantity of these healing cells in the early phase of tendon repair. Unfortunately, these helpful cells normally disappear with time. Therefore prolonging their presence is advantageous. Also increased type I & III collagen and macrophages were increased; supporting that PRP promotes tendon healing
http://www3.interscience.wiley.com/cgi-bin/abstract/117880365/ABSTRACT?CRETRY=1&SRETRY=0
Tags: collagen, growth factors, natural healing, pateller tendon, platelet rich plasma, tendon injuries, tendonopathy
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Founder of the Orthohealing Center, Dr. Sampson is a recognized expert on orthobiologics and regenerative medicine. He lectures internationally and spearheads OHC’s clinical research efforts. Dr. Sampson is a Clinical Instructor of Medicine at The David Geffen School of Medicine at UCLA, and is a Clinical Assistant Professor of Physical Medicine & Rehabilitation, Western University of Health Sciences.
Thursday, January 3rd, 2008 by Steven Sampson D.O.
A growing number of physicians are using musculoskeletal ultrasound to guide various injections. As a leading imaging technique in Europe, ultrasound is safe, economic, convenient, & effective in diagnosing many injuries. The technology has dramatically improved and allows us to visualize nerve & tendon fibers. While the quality is not quite MRI caliber, ultrasound allows for dynamic (motion studies). In other words, ultrasound allows functional evaluation of an injury with movement, whereas MRI takes a still image. Also, ultrasound has color doppler that shows areas of blood flow changes (called neo vascularization). This allows us to deliver the PRP within a millimeter of the target site, or even discover other regions that are affected. 
Ultrasound technology continues to grow. I just upgraded to this Sonosite portable machine with color doppler.
Tags: musculoskeletal ultrasound, osteoarthritis, platelet rich plasma, PRP, tendon injuries
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Founder of the Orthohealing Center, Dr. Sampson is a recognized expert on orthobiologics and regenerative medicine. He lectures internationally and spearheads OHC’s clinical research efforts. Dr. Sampson is a Clinical Instructor of Medicine at The David Geffen School of Medicine at UCLA, and is a Clinical Assistant Professor of Physical Medicine & Rehabilitation, Western University of Health Sciences.
